Before taking selegiline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Selegiline (Selegiline HCl) should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain kind of adrenal gland tumor (pheochromocytoma), cerebrovascular disease (e.g., stroke), heart problems (e.g., congestive heart failure, heart attack), high blood pressure, history of severe/frequent headaches, peptic ulcer.
Before using Selegiline (Selegiline HCl), tell your doctor or pharmacist your medical history, especially of: bleeding problems, diabetes, personal/family history of mental/mood disorders (e.g., schizophrenia, bipolar disorder), family history of high blood pressure, heart disease (e.g., coronary artery disease, history of chest pain), liver disease, history of peptic ulcer, overactive thyroid (hyperthyroidism).
Selegiline (Selegiline HCl) may make you dizzy; use caution while engaging in activities requiring alertness such as driving or using machinery. Avoid alcoholic beverages.
To minimize dizziness and the risk of fainting, get up slowly when rising from a sitting or lying position.
Before having surgery, tell your doctor or dentist you are taking Selegiline (Selegiline HCl). You may need to stop taking Selegiline (Selegiline HCl) beforehand. Follow your doctor's instructions carefully.
Selegiline should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
It is not known if Selegiline (Selegiline HCl) passes into breast milk. Consult your doctor before breast-feeding.
IMPORTANT NOTE: This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
IMPORTANT NOTE: This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.
Take Selegiline (Selegiline HCl) by mouth, usually twice daily with breakfast and lunch. Taking selegiline late in the day may cause trouble sleeping. Dosage of Selegiline (Selegiline HCl) is based on your medical condition and response to therapy. The usual highest dose is 5 milligrams twice a day. Do not increase your dose or take it more often than directed.
After you have been taking selegiline for 2 or 3 days, your doctor may direct you to lower your levodopa dose. Follow your doctor's instructions closely. Do not stop or change the dose of any of your medications without first talking with your doctor.
It may take a few weeks for the full benefits of the drug to be noticed. Do not stop taking Selegiline (Selegiline HCl) without first consulting your doctor. Talk with your doctor if the medication stops working well or if your condition worsens.
IMPORTANT NOTE: This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.
Dizziness, abdominal pain, dry mouth, nausea, stomach upset, trouble sleeping, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
If you are also taking levodopa, you may experience more side effects from the levodopa when taking selegiline. Tell your doctor immediately if any of these side effects occur: nausea, shakiness, muscle stiffness, mental/mood changes such as hallucinations/abnormal dreams. Your doctor may need to change your medication or dose. Do not stop or change the dose of your levodopa without talking with your doctor first.
Remember that your doctor has prescribed Selegiline (Selegiline HCl) because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Selegiline (Selegiline HCl) do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, loss of balance, mental/mood changes (e.g., agitation, confusion, depression, hallucinations), worsening muscle stiffness/twitching, changes in sexual ability/interest, increased shaking (tremor), swollen ankles/legs, difficulty urinating, unusual weight gain.
Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, black/tarry stools, vomit that looks like coffee grounds.
Selegiline (Selegiline HCl) may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many drug and food interactions can increase this risk. (See also Drug Interactions section.) Seek immediate medical attention if any of these serious side effects occur: frequent/severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, severe nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision changes (e.g., double/blurred vision)., sudden sensitivity to light (photophobia).
A serious allergic reaction to Selegiline (Selegiline HCl) is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
IMPORTANT NOTE: This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.
If you miss a dose of Selegiline (Selegiline HCl), take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
IMPORTANT NOTE: This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.
Selegiline (Selegiline HCl) should not be used with the following medications because very serious (possibly fatal) interactions may occur: antidepressants (e.g., TCAs such as amitriptyline/protriptyline, nefazodone, SSRIs such as fluoxetine/paroxetine/sertraline, venlafaxine), appetite suppressants (e.g., diethylpropion, sibutramine), drugs for attention deficit disorder (e.g., atomoxetine, methylphenidate), certain antihistamines (azatadine, carbetapentane, chlorpheniramine), bronchodilators (e.g., albuterol, salmeterol), bupropion, buspirone, carbamazepine, cyclobenzaprine, dextromethorphan, certain drugs for glaucoma (e.g., apraclonidine, brimonidine), certain drugs for high blood pressure (e.g., guanethidine, methyldopa), other MAO inhibitors (furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, tranylcypromine), nasal decongestants (e.g., phenylephrine, pseudoephedrine), certain narcotic medications (e.g., fentanyl, meperidine), street drugs (e.g., MDMA/"ecstasy", LSD, mescaline), stimulants (e.g., amphetamines, ephedrine, epinephrine, phenylalanine), "triptan" migraine drugs (e.g., sumatriptan, rizatriptan), tramadol, tyrosine, tryptophan.
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting selegiline. Do not take these medications within the 2 weeks before, during or after treatment with selegiline. If you have been taking fluoxetine, wait at least 5 weeks after stopping fluoxetine before starting selegiline. Discuss with your doctor how much time to wait between starting or stopping any of these drugs and taking selegiline.
Before using Selegiline (Selegiline HCl), tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs for diabetes (e.g., glyburide, insulin), drugs for high blood pressure (e.g., beta blockers such as atenolol, clonidine, rauwolfia alkaloids such as reserpine, "water pills"/diuretics such as hydrochlorothiazide), herbal products (e.g., ginseng, ephedra/ma huang).
Check the labels on all your medicines (e.g., allergy, cough-and-cold products, diet pills) because they may contain dextromethorphan, decongestants, or stimulants. Ask your pharmacist about the safe use of those products.
To prevent a very serious high blood pressure reaction, it is very important that you follow a special diet recommended by your doctor or dietician in order to limit your intake of tyramine while you are taking this medicine. Avoid foods and beverages that are high in tyramine, including: aged cheeses (e.g., bleu, cheddar, parmesan), dried/aged/fermented meats and sausages (e.g., salami, liverwurst), preserved fish (e.g., pickled herring), products containing large amounts of yeast (e.g., concentrated yeast extract, bouillon cubes, powdered soup/gravy, homemade or sourdough bread), fermented foods (e.g., sauerkraut, kim chee), most soybean products (e.g., soy sauce, tofu), broad/fava beans, red wine, sherry, tap beers, vermouth. Limit or avoid foods that are moderate in tyramine, including: avocados, bananas, eggplant, green beans, raisins, raspberries, red plums, spinach, tomatoes, chocolate, cultured dairy products (e.g., buttermilk, yogurt, sour cream), fish eggs, pate, peanuts, coffee, cola, alcohol-free beer, bottled beer, distilled spirits, port, white wine. Consult your doctor or dietician for more details and a complete list of other tyramine-containing foods you should limit or avoid. Seek immediate medical attention if you notice symptoms of very high blood pressure such as unusually fast/slow heartbeat, vomiting, unexplained sweating, headache, chest pain, sudden vision changes, weakness on one side of the body, slurred speech.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
IMPORTANT NOTE: This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.