Animals should be tested for heartworm disease prior to beginning the administration of Revolution.  The appropriate dosage must be used to achieve the desired results.  Revolution should not be applied to sick, malnourished, or underweight animals.  Do not apply Revolution to wet hair and wait at least 2 hours after application to bathe an animal.  Humans should be careful to avoid direct contact with Revolution and wash hands immediately after administering the product as increased skin sensitivity has been noted in humans.  Revolution can also cause eye irritation.

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

Revolution must be stored in a safe place, out of the reach of children, at temperatures below 30 degrees Centigrade or 86 degrees Fahrenheit.

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

Revolution is a topical veterinary medication to control fleas, ticks, and certain intestinal parasites in dogs and cats.  The active ingredient in Revolution is selamectin, a macrocyclic lactone compound which comes as a yellow to colorless liquid in prepackaged single dose tubes.  It is applied directly to the hair between the shoulder blades of dogs age 6 weeks and greater and cats 8 weeks of age or more.  

Revolution is used to kill and prevent fleas and ticks on dogs and cats along with treating mange and ear mites in dogs.  It prevents heartworms in dogs and cats and treats and controls round worms in cats along with preventing hook worms in cats.  The drug must be applied at monthly intervals to prevent worm infestations, especially in the case of heartworms in areas where mosquitoes are endemic.

Revolution is absorbed through the animal's skin where blood concentrations of selamectin prevent heartworm disease, and fight fleas, ticks, and parasitic worms.  

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

Each tube of Revolution is formulated to provide a minimum of 2.7 mg/lb or 6 mg/kg of body weight of selamectin.  The tubes are packaged in dosages for animals from 5 pounds and under up to 130 pounds.  For dogs greater than 130 pounds a combination of two tubes equal to the appropriate weight strength is recommended.  Do not split a tube into two or more doses as this may result in too much or too little product being applied.

To apply, press the cap into the tube to break open the applicator.  Part the hair of the animal between the shoulder blades to expose the skin.  After removing the cap, apply all of the appropriate size tube on to the skin of the animal by squeezing the tube four or five times to empty it.  If you do not understand how to apply Revolution, ask your veterinarian to demonstrate.

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

Temporary hair loss, matting of the hair, and discoloration of the hair can be observed along with skin irritation at the application site.  Drooling, loss of appetite, diarrhea, incoordination, muscle tremors, rapid breathing and rapid heart rate can also be seen.

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

If an overdose is applied, seek veterinary care immediately.  Symptoms of an overdose can include increased salivation, incoordination, loss of appetite, vomiting, diarrhea, rapid breathing, and rapid heart rate.  If a dose is missed apply it as soon as this is realized but only apply a single dose, never two in one month.

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

Revolution should not be applied to pets receiving other heartworm medications.  It is not know to interact with other veterinary products such as antiworm preparations, vaccines, antibiotics, steroids, collars, or shampoos.

IMPORTANT NOTE:  This information is provided for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.